Research Professor in Medicine
Associate Director, Center for Applied Research Sciences
Director, Clinical Science Research Core of the Nutrition and Obesity Research Center (NORC)
During her work with Dr. Klein, and in large part stimulated by her BIRCWH award, Dr. Mittendorfer has been studying the sexual dimorphism in metabolism. She has conducted numerous studies to determine the differences between men and women in their responses to lifestyle, pharmacologic, and nutritional interventions. These studies have monitored body composition, functional performance, insulin responsiveness, fatty acid and muscle protein metabolism, as well as intracellular signaling pathways. One of her recent studies highlighted that muscle protein synthesis stimulated by regular exercise is blunted in elderly women when compared to elderly men. This may be in part due to differences in leucine-mediated mTOR activation (Diabetes, in press). She has published more than 100 papers and has trained research fellows and junior faculty members in her role as Director of the of the Clinical Science Research Core within the NIH-funded Nutrition and Obesity Research Center at Washington University.
BIRCWH Scholar from 08/01/2000 until 02/29/2004